AMD and Anthropic have announced a strategic partnership that will see up to 2GW of AMD Instinct MI450 Series GPUs deployed in AMD Helios rack-scale solutions. Building on the AI company’s existing use of Instinct MI355X GPUs, the new deployment of the first gigawatt scheduled to begin in the first half of 2027.
AMD Extends Partnership With Anthropic
Beyond the hardware deployment, AMD and Anthropic are launching a multi-year engineering collaboration centered on using Anthropic’s Claude AI model to optimize workloads for AMD Instinct GPUs and accelerate development of the ROCm software stack. The collaboration also includes AMD broadly adopting Claude across its own engineering and product development teams; on top of that, the chipmaker has also committed to a strategic equity investment of up to $5 billion in Anthropic as part of this agreement.
The AMD Instinct MI450 Series GPUs targeted for this deployment are paired with AMD’s Helios rack-scale solutions, which are designed for large-scale AI training and inference workloads. Besides the new GPUs, the hardware includes AMD EPYC “Venice” CPUs, AMD Pensando DPUs, and of course, the aforementioned ROCm software stack.
“We are thrilled to deepen our partnership with Anthropic and deploy AMD Helios at gigawatt scale,” said Dr. Lisa Su, AMD president and CEO. “This collaboration brings together Anthropic’s leadership in frontier AI with the full strength of AMD high-performance computing. Together, we will accelerate AI adoption at scale and establish Helios as a major platform for the next generation of AI infrastructure.”
“Access to compute is central to keeping Claude at the frontier and meeting demand from our customers,” said Tom Brown, co-founder and chief compute officer of Anthropic. “By partnering with AMD across the stack, we are securing the capacity we need and optimizing it for training and serving Claude. Running across a diversified range of hardware lets us map the right workloads to the right hardware.”
Pokdepinion: More money into the proverbial AI black hole, which is very on-brand with today’s tech companies.

